Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ROS1 | P08922 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27716275 | 0.92 | PPARG (0.40) | PPARGHPGDROS1ALKGPR84 | |
| SCHEMBL27716322 | 0.92 | PPARG (0.41) | PPARGROS1ALKNPC1RAB9A | |
| SCHEMBL27716263 | 0.89 | PPARG (0.45) | PPARG | |
| SCHEMBL27716405 | 0.89 | PPARG (0.41) | PPARGHPGDROS1ALKNPC1 | |
| SCHEMBL27737216 | 0.88 | PPARG (0.40) | PPARGHPGDROS1ALKNPC1 | |
| SCHEMBL27737206 | 0.86 | PPARG (0.41) | PPARGHPGDROS1ALKGPR84 | |
| SCHEMBL27716255 | 0.85 | PPARG (0.44) | PPARG | |
| SCHEMBL27737194 | 0.83 | P2RX3 (0.41) | PPARGHPGDROS1ALKNPC1 | |
| SCHEMBL27716279 | 0.81 | PPARG (0.44) | PPARGSCN9AALDH1A1 | |
| SCHEMBL27737205 | 0.81 | PPARG (0.43) | PPARGNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101282725-A | Therapeutic agent for diabetes | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2008-10-08 | — | — | CN | disclosed |