Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 5/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14264190 | 0.85 | MAPT (0.55) | MAPTHSD11B1TLR8BCL2L1MCL1 | |
| SCHEMBL10573534 | 0.82 | MAPK14 (0.52) | GSK3BEZH2PTPN1LMNAMAPK14 | |
| SCHEMBL14264193 | 0.81 | TLR8 (0.55) | MAPTHSD11B1TLR8BCL2L1MCL1 | |
| SCHEMBL12780756 | 0.77 | TLR8 (0.67) | MAPTHSD11B1TLR8BCL2L1MCL1 | |
| SCHEMBL12122765 | 0.76 | TLR8 (0.58) | MAPTHSD11B1TLR8BCL2L1MCL1 | |
| SCHEMBL6177743 | 0.75 | TLR8 (0.56) | MAPTHSD11B1TLR8BCL2L1MCL1 | |
| SCHEMBL22169507 | 0.75 | HSD11B1 (0.57) | MAPTHSD11B1TLR8BCL2L1MCL1 | |
| SCHEMBL14264189 | 0.74 | MAPT (0.69) | MAPTHSD11B1TLR8BCL2L1MCL1 | |
| SCHEMBL12806825 | 0.74 | HSD11B1 (0.57) | MAPTHSD11B1TLR8BCL2L1MCL1 | |
| SCHEMBL11508991 | 0.73 | TLR8 (0.52) | MAPTHSD11B1TLR8BCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110059970-A1 | 4-PHENYL-1,3-THIAZOLES AND 4-PHENYL-1,3-OXAZOLES DERIVATIVES AS CANNABINOID RECEPTOR LIGANDS | IPSEN PHARMA S.A.S. (FR) | 2011-03-10 | — | — | US | disclosed |
| EP-2201007-A1 | CANNABINOID RECEPTOR LIGANDS | IPSEN PHARMA S.A.S. (FR) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009071753-A1 | CANNABINOID RECEPTOR LIGANDS | IPSEN PHARMA S.A.S. (FR) | 2009-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059970-A1 | 4-PHENYL-1,3-THIAZOLES AND 4-PHENYL-1,3-OXAZOLES DERIVATIVES AS CANNABINOID RECEPTOR LIGANDS | CNR1, CNR2, NPY1R | MAPT 2207/4885HSD11B1 1675/4885TLR8 1488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.