Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.55 |
| ▸ | ACLY | P53396 | 4/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4220421 | 0.86 | MAPT (0.49) | MAPTALOX15AKR1C3AKR1C2ACLY | |
| SCHEMBL28649151 | 0.84 | MAPT (0.81) | MAPTALOX15SIRT2SIRT1KDM4E | |
| SCHEMBL4223119 | 0.84 | AKR1C3 (0.60) | MAPTAKR1C3AKR1C2ACLYSIRT2 | |
| SCHEMBL27985224 | 0.84 | SIRT2 (0.53) | MAPTALOX15AKR1C3AKR1C2ACLY | |
| SCHEMBL8529851 | 0.84 | MAPT (0.74) | MAPTALOX15AKR1C3AKR1C2SIRT2 | |
| SCHEMBL13877053 | 0.84 | SLC6A4 (0.50) | MAPTALOX15AKR1C3AKR1C2ACLY | |
| SCHEMBL27388926 | 0.83 | MAPT (0.69) | MAPTALOX15AKR1C3AKR1C2SIRT2 | |
| SCHEMBL3236732 | 0.83 | MAPT (0.69) | MAPTALOX15AKR1C3AKR1C2SIRT2 | |
| SCHEMBL4217099 | 0.83 | ABCG2 (0.46) | MAPTALOX15AKR1C3AKR1C2ACLY | |
| SCHEMBL25063305 | 0.82 | MAPT (0.67) | MAPTALOX15AKR1C3AKR1C2SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101094829-B | novel anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO.,LTD. (JP) | 2012-02-08 | — | — | CN | disclosed |
| CN-101094829-A | Novel anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO LTD (JP) | 2007-12-26 | — | — | CN | disclosed |