Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.81 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | FABP4 | P15090 | 1/20 | 0.51 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12109319 | 0.97 | MAPT (0.81) | MAPTALOX15SIRT2KDM4EPOLB | |
| SCHEMBL13224505 | 0.92 | MAPT (0.89) | MAPTALOX15SIRT2KDM4EPOLB | |
| SCHEMBL31914 | 0.90 | MAPT (1.00) | MAPTALOX15SIRT2KDM4EPOLB | |
| SCHEMBL12109338 | 0.89 | MAPT (0.69) | MAPTALOX15SIRT2KDM4EPOLB | |
| SCHEMBL1301699 | 0.89 | MAPT (0.69) | MAPTALOX15SIRT2KDM4EPOLB | |
| SCHEMBL22445145 | 0.86 | MAPT (0.79) | MAPTALOX15SIRT2KDM4EPOLB | |
| SCHEMBL31168050 | 0.86 | MAPT (0.79) | MAPTALOX15SIRT2KDM4EPOLB | |
| SCHEMBL28658698 | 0.85 | MAPT (0.78) | MAPTALOX15SIRT2KDM4EPOLB | |
| SCHEMBL27716618 | 0.84 | MAPT (0.67) | MAPTALOX15SIRT2KDM4EPOLB | |
| SCHEMBL12605599 | 0.84 | MAPT (0.76) | MAPTALOX15SIRT2KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073468-A | Preparation and application of imidazopyrazine BTK inhibitor | 药雅科技(上海)有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-113631548-A | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2021-11-09 | — | — | CN | disclosed |