Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 17/20 | 0.74 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.74 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1038520 | 0.91 | CYP11B2 (0.73) | CYP11B2CYP19A1CYP11B1 | |
| SCHEMBL31326495 | 0.89 | CYP11B2 (0.75) | CYP11B2CYP19A1CYP11B1 | |
| SCHEMBL1037525 | 0.88 | CYP11B2 (0.81) | CYP11B2CYP19A1CYP11B1 | |
| SCHEMBL1041216 | 0.87 | CYP11B2 (0.81) | CYP11B2CYP19A1CYP11B1 | |
| SCHEMBL1040100 | 0.85 | CYP11B2 (1.00) | CYP11B2CYP19A1CYP11B1 | |
| SCHEMBL1039095 | 0.85 | CYP11B2 (1.00) | CYP11B2CYP19A1CYP11B1 | |
| SCHEMBL1040315 | 0.84 | CYP11B2 (0.69) | CYP11B2CYP19A1CYP11B1P2RX7 | |
| SCHEMBL1040314 | 0.83 | CYP11B2 (0.67) | CYP11B2CYP19A1CYP11B1 | |
| SCHEMBL13563942 | 0.82 | CYP11B2 (0.80) | CYP11B2CYP19A1CYP11B1 | |
| SCHEMBL1041635 | 0.82 | CYP11B2 (0.79) | CYP11B2CYP19A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248078-A | Fused imidazo derivatives inhibiting aldosterone synthase and aromatase | NOVARTIS AG (CH) | 2008-08-20 | — | — | CN | disclosed |