Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.53 |
| ▸ | CKS1B | P61024 | 2/20 | 0.51 |
| ▸ | SKP1 | P63208 | 2/20 | 0.51 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.46 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2227063 | 0.80 | GPR119 (0.56) | GPR119CKS1BSKP1SKP2MAP4K4 | |
| SCHEMBL4316079 | 0.80 | CKS1B (0.55) | GPR119CKS1BSKP1SKP2MAP4K4 | |
| SCHEMBL12964697 | 0.80 | GPR119 (0.79) | GPR119CKS1BSKP1SKP2MAP4K4 | |
| SCHEMBL38663361 | 0.79 | CKS1B (0.49) | GPR119CKS1BSKP1SKP2MAP4K4 | |
| SCHEMBL18790713 | 0.79 | CKS1B (0.49) | GPR119CKS1BSKP1SKP2MAP4K4 | |
| SCHEMBL29473497 | 0.78 | TRPV1 (0.57) | GPR119CKS1BSKP1SKP2MAP4K4 | |
| SCHEMBL20140603 | 0.78 | TRPV1 (0.57) | GPR119CKS1BSKP1SKP2MAP4K4 | |
| SCHEMBL23560770 | 0.78 | CKS1B (0.57) | GPR119CKS1BSKP1SKP2MAP4K4 | |
| SCHEMBL15114941 | 0.78 | CKS1B (0.48) | GPR119CKS1BSKP1SKP2MAP4K4 | |
| SCHEMBL28101296 | 0.78 | CKS1B (0.50) | GPR119CKS1BSKP1SKP2MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101146796-A | 3-(indazol-5-yl)-(1,2,4)triazine derivatives and related compounds as protein kinase inhibitors for the treatment of cancer | SCHERING CORP (US) | 2008-03-19 | — | — | CN | disclosed |