Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12191226 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL27467903 | 0.80 | MAPT (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1879440 | 0.78 | MEN1 (0.51) | SMN1; SMN2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6756946 | 0.78 | FGFR1 (0.50) | SMN1; SMN2FGFR1ALDH1A1HPNKEAP1 | |
| SCHEMBL1880372 | 0.77 | TP53 (0.48) | SMN1; SMN2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2498081 | 0.76 | MLLT3 (0.46) | SMN1; SMN2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2493717 | 0.76 | ALDH1A1 (0.50) | SMN1; SMN2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14977404 | 0.76 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1HSP90AA1CCR6PDE4B | |
| SCHEMBL2497173 | 0.75 | MLLT3 (0.46) | SMN1; SMN2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3772778 | 0.75 | FGFR1 (0.50) | FGFR1ALDH1A1HPNKEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101282942-A | Imidazole derivatives for the treatment of anxiety and related diseases | NEUROSEARCH AS (DK) | 2008-10-08 | — | — | CN | disclosed |