Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | LCK | P06239 | 3/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.43 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5998031 | 0.90 | LCK (0.62) | RAB9AL3MBTL1LCKMAPK14SRC | |
| SCHEMBL5998192 | 0.77 | SRC (0.47) | SRCMAPK1WNT3AWEE1 | |
| SCHEMBL5997162 | 0.75 | MAPT (0.48) | L3MBTL1SRCCYP1A2LMNAMAPT | |
| SCHEMBL5997660 | 0.75 | LCK (0.55) | LCKMAPK14SRCWEE1 | |
| SCHEMBL12190166 | 0.74 | CYP11B2 (0.63) | RAB9AMAPTMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL5997282 | 0.74 | SRC (0.59) | LCKMAPK14PPARGSRCLMNA | |
| SCHEMBL4967865 | 0.73 | MAPK8 (0.49) | RAB9AL3MBTL1CHRM1LMNAMAPT | |
| SCHEMBL5997109 | 0.73 | ABL1 (0.63) | LCKMAPK14SRCKDRPKMYT1 | |
| SCHEMBL399009 | 0.72 | SMO (0.56) | RAB9AL3MBTL1CHRM1LMNAMAPT | |
| SCHEMBL5996482 | 0.71 | SRC (0.51) | RAB9ALCKMAPK14SRCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101155799-A | Pyrimidine inhibitors of kinases | TARGEGEN INC (US) | 2008-04-02 | — | — | CN | disclosed |