Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Piperazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312465 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL27634057 | 0.92 | — | — | |
| Piperazine SCHEMBL28208895 | 0.89 | HRH4 (0.31) | — | |
| SCHEMBL743262 | 0.82 | — | — | |
| SCHEMBL28347353 | 0.81 | — | — | |
| SCHEMBL6623701 | 0.81 | — | — | |
| SCHEMBL1000740 | 0.81 | — | — | |
| SCHEMBL9638785 | 0.79 | NISCH (0.32) | — | |
| Quinoxaline SCHEMBL28592780 | 0.79 | MEN1 (0.31) | — | |
| Methylamine SCHEMBL8761530 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214414-B | The diamine derivative of opticity and manufacture method thereof | SANKYO CO. (JP) | 2016-02-17 | — | — | CN | disclosed |
| CN-103214414-A | Optically active diamine derivative and process for producing the same | DAIICHI SANKYO CO LTD | 2013-07-24 | — | — | CN | disclosed |
| CN-101263110-B | Optically active diamine derivative and process for producing the same | DAIICHI SANKYO CO LTD | 2013-04-03 | — | — | CN | disclosed |
| CN-102393361-A | Method for evaluating authenticity of product and handheld device for verifying product | ORSON DIX CO LTD | 2012-03-28 | — | — | CN | disclosed |
| CN-101772420-A | Verification of a product | AUTHENTIX INC | 2010-07-07 | — | — | CN | disclosed |
| CN-101263110-A | Optically active diamine derivative and process for producing the same | DAIICHI SANKYO CO LTD (JP) | 2008-09-10 | — | — | CN | disclosed |