⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27634057 | 0.98 | — | — | |
| Piperazine SCHEMBL27718655 | 0.94 | SLC18A3 (0.31) | — | |
| SCHEMBL743262 | 0.88 | — | — | |
| SCHEMBL28347353 | 0.86 | — | — | |
| SCHEMBL1000740 | 0.86 | — | — | |
| SCHEMBL9638785 | 0.84 | NISCH (0.32) | — | |
| Quinoxaline SCHEMBL28592780 | 0.83 | MEN1 (0.31) | — | |
| Methylamine SCHEMBL8761530 | 0.83 | — | — | |
| Piperazine SCHEMBL28208895 | 0.83 | HRH4 (0.31) | — | |
| Oxazole SCHEMBL27760674 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1303 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134035-B | 3- (1H-imidazol-2-yl) -2,3,8 a-tetrahydroindol-5 (1H) -one derivatives useful as factor XIA inhibitors | 詹森药业有限公司 | 2025-03-11 | — | — | CN | claimed |
| US-12239655-B2 | Combined modalities for nucleosides and/or NADPH oxidase (NOX) inhibitors as myeloid-specific antiviral agents | EMORY UNIVERSITY (US) | 2025-03-04 | — | — | US | claimed |
| US-12030867-B2 | Hsp90β selective inhibitors | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2024-07-09 | — | — | US | claimed |
| CN-118239923-A | Compounds useful as inhibitors of factor XIIa, pharmaceutical compositions and uses thereof | 合肥工业大学 | 2024-06-25 | — | — | CN | claimed |
| EP-4228630-A1 | NLRP3 ACTIVATORS FOR USE IN THE TREATMENT OF INFECTIOUS DISEASES OR CANCER BY ACTIVATING NLRP3 INFLAMMASOME | Albert-Ludwigs-Universität Freiburg (DE) | 2023-08-23 | — | — | EP | claimed |
| WO-2023036289-A1 | HYDROXAMIC ACID COMPOUND HAVING ENPP1 INHIBITORY ACTIVITY AND USE THEREOF | 上海海和药物研究开发股份有限公司 | 2023-03-16 | — | — | WO | claimed |
| US-20220213114-A1 | PYRANOPYRAZOLE AND PYRAZOLOPYRIDINE IMMUNOMODULATORS FOR TREATMENT OF AUTOIMMUNE DISEASES | THE ROCKEFELLER UNIVERSITY (US) | 2022-07-07 | — | — | US | claimed |
| US-11312723-B2 | Pyranopyrazole and pyrazolopyridine immunomodulators for treatment of autoimmune diseases | THE ROCKEFELLER UNIVERSITY (US) | 2022-04-26 | — | — | US | claimed |
| WO-2022079246-A1 | NLRP3 ACTIVATORS FOR USE IN THE TREATMENT OF INFECTIOUS DISEASES OR CANCER BY ACTIVATING NLRP3 INFLAMMASOME | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2022-04-21 | — | — | WO | claimed |
| CN-109475530-B | Aminoacyl indazole immunomodulators for treating autoimmune diseases | 洛克菲勒大学 | 2022-03-01 | — | — | CN | claimed |
| WO-1999043666-A1 | PHOTOCHROMATIC COMPOSITIONS ENDOWED WITH LIGHT FATIGUE RESISTANCE AND PHOTOCHROMATIC ARTICLES CONTAINING THEM | GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) | 1999-09-02 | — | — | WO | claimed |
| WO-1999001457-A1 | PHOTOCHROMATIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN POLYMERIC MATERIALS | GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) | 1999-01-14 | — | — | WO | claimed |
| US-5399539-A | Chromium, pyrrole and aluminum compounds on supports, recovering and activation | PHILLIPS PETROLEUM COMPANY (US) | 1995-03-21 | — | — | US | claimed |
| EP-0117961-B1 | HETEROCYCLIC DERIVATIVES SUBSTITUTED BY AN AMINO RADICAL, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Albert ROLLAND S.A. Société dite (FR) | 1991-04-03 | — | — | EP | claimed |
| US-4737586-A | Process for the preparation of bis-indolic compounds | AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (FR) | 1988-04-12 | — | — | US | claimed |
| CN-86103278-A | The method for preparing heterocyclic amide derivative | — | 1986-12-17 | — | — | CN | claimed |
| EP-0022634-B1 | ACYLATED INDOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS AND DRUGS COMPRISING THEM | TEIJIN LIMITED (JP) | 1983-04-06 | — | — | EP | claimed |
| EP-0022634-A1 | Acylated indole derivatives, processes for their preparation and pharmaceutical compositions and drugs comprising them | TEIJIN LIMITED (JP) | 1981-01-21 | — | — | EP | claimed |
| US-4174453-A | HYDROGENATION, ACIDFICATION | ENDO LABORATORIES, INC. (US) | 1979-11-13 | — | — | US | claimed |
| US-4137042-A | FLUORESCENT BRIGHTENERS, INDICATOR DYES | CIBA-GEIGY AG (CH) | 1979-01-30 | — | — | US | claimed |