SCHEMBL2771867

SCHEMBL2771867

COC(=O)c1cc(C(=O)OC)cc(S(=O)(=O)OCCC[PH](c2ccccc2)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.40
LMNA P02545 1/20 0.40
POLB P06746 1/20 0.39
TSHR P16473 1/20 0.39
ALDH1A1 P00352 6/20 0.38
KDM4E B2RXH2 4/20 0.38
GAA P10253 1/20 0.38
PKM P14618 1/20 0.38
RAB9A P51151 2/20 0.37
PSMD10 O75832 1/20 0.37
MAPT P10636 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
CTSG P08311 1/20 0.36
CMA1 P23946 1/20 0.36
HIF1A Q16665 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2769026 0.93 POLB (0.41) HPGDLMNAPOLBTSHRALDH1A1
SCHEMBL3900970 0.81 L3MBTL1 (0.44) HPGDLMNAPOLBTSHRALDH1A1
SCHEMBL9440613 0.76 TSHR (0.46) HPGDLMNAPOLBTSHRALDH1A1
SCHEMBL9440792 0.75 L3MBTL1 (0.43) HPGDLMNAPOLBTSHRALDH1A1
SCHEMBL9440360 0.75 L3MBTL1 (0.43) HPGDLMNAPOLBTSHRALDH1A1
SCHEMBL3910145 0.75 TSHR (0.42) HPGDLMNAPOLBTSHRALDH1A1
SCHEMBL2769061 0.74 L3MBTL1 (0.36) HPGDLMNAPOLBALDH1A1KDM4E
SCHEMBL6555898 0.73 HPGD (0.44) HPGDLMNAPOLBTSHRALDH1A1
SCHEMBL10484409 0.72 TSHR (0.60) HPGDLMNAPOLBTSHRALDH1A1
SCHEMBL3915612 0.71 TSHR (0.47) HPGDLMNAPOLBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1929375-B1 BIASABLE TRANSFER MEMBER EASTMAN KODAK CO (US) 2010-04-28 EP disclosed
US-7540981-B2 Biasable transfer composition and member EASTMAN KODAK COMPANY (US) 2009-06-02 US disclosed
EP-1929375-A1 BIASABLE TRANSFER COMPOSITION AND MEMBER EASTMAN KODAK COMPANY (US) 2008-06-11 EP disclosed
WO-2007041054-A1 BIASABLE TRANSFER COMPOSITION AND MEMBER EASTMAN KODAK COMPANY (US) 2007-04-12 WO disclosed
US-20070075298-A1 Biasable transfer composition and member EASTMAN KODAK COMPANY 2007-04-05 US disclosed