SCHEMBL27719953

SCHEMBL27719953

CCCCCCCCCCOc1ccc([N+](=O)[O-])cc1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 6/20 0.58
CYSLTR2 Q9NS75 1/20 0.57
CYSLTR1 Q9Y271 1/20 0.57
MAPT P10636 3/20 0.49
LMNA P02545 2/20 0.49
NPSR1 Q6W5P4 2/20 0.49
ALDH1A1 P00352 1/20 0.49
KMT2A Q03164 1/20 0.49
THRA P10827 1/20 0.48
THRB P10828 1/20 0.48
CNR1 P21554 1/20 0.47
ACHE P22303 1/20 0.47
CNR2 P34972 1/20 0.47
RAB9A P51151 2/20 0.47
S1PR2 O95136 1/20 0.46
S1PR1 P21453 1/20 0.46
S1PR3 Q99500 1/20 0.46
LPAR2 Q9HBW0 1/20 0.46
NPC1 O15118 1/20 0.46
CYP1A2 P05177 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9699858 1.00 CYP19A1 (0.58) CYP19A1CYSLTR2CYSLTR1MAPTLMNA
SCHEMBL27735670 0.94 MAPT (0.51) CYP19A1CYSLTR2CYSLTR1MAPTLMNA
SCHEMBL27714825 0.90 CYP19A1 (0.56) CYP19A1CYSLTR2CYSLTR1MAPTLMNA
SCHEMBL29163212 0.89 CYP19A1 (0.62) CYP19A1CYSLTR2CYSLTR1MAPTLMNA
SCHEMBL9697432 0.89 CYP19A1 (0.62) CYP19A1CYSLTR2CYSLTR1MAPTLMNA
SCHEMBL9699836 0.89 CYP19A1 (0.62) CYP19A1CYSLTR2CYSLTR1MAPTLMNA
SCHEMBL7695074 0.87 CYP19A1 (0.60) CYP19A1CYSLTR2CYSLTR1MAPTLMNA
SCHEMBL9127581 0.87 CYP19A1 (0.66) CYP19A1CYSLTR2CYSLTR1MAPTLMNA
SCHEMBL30292299 0.87 CYP19A1 (0.66) CYP19A1CYSLTR2CYSLTR1MAPTLMNA
SCHEMBL9165752 0.87 CYP19A1 (0.66) CYP19A1CYSLTR2CYSLTR1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101298419-B Preparation of 3-ethoxy-4-decyloxy nitrobenzene ZHEJIANG GENEBEST PHARMACEUTICAL CO LTD 2010-05-12 CN claimed
CN-101298419-A Preparation of 3-ethoxy-4-decyloxy nitrobenzene FUYANG GENEBEST CHEMICAL INDUS (CN) 2008-11-05 CN claimed
CN-101298419-B Preparation of 3-ethoxy-4-decyloxy nitrobenzene ZHEJIANG GENEBEST PHARMACEUTICAL CO LTD 2010-05-12 CN disclosed
CN-101298419-A Preparation of 3-ethoxy-4-decyloxy nitrobenzene FUYANG GENEBEST CHEMICAL INDUS (CN) 2008-11-05 CN disclosed