Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 9/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 9/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27420449 | 0.81 | ABL1 (0.49) | LMNAKDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL27605356 | 0.77 | KDM4E (0.64) | LMNAKDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL1285263 | 0.74 | SMN1; SMN2 (0.64) | LMNAKDM4EALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL12305003 | 0.72 | ALDH1A1 (0.45) | LMNAKDM4EALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL31258831 | 0.72 | CA12 (0.65) | LMNAKDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL330670 | 0.72 | CA12 (0.65) | LMNAKDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL2054476 | 0.72 | HDAC8 (0.51) | LMNAKDM4EALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL30034172 | 0.70 | KDM4E (0.60) | LMNAKDM4EALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL4261271 | 0.70 | KMT2A (0.47) | LMNAKDM4EALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL4462421 | 0.70 | ALDH1A1 (0.57) | LMNAKDM4EALDH1A1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101160285-A | Substituted sulfonylaminoarylmethyl cyclopropanecarboxamide as vr1 receptor antagonists | PFIZER (US) | 2008-04-09 | — | — | CN | disclosed |