Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969352 | 0.80 | EPHX2 (0.57) | EPHX2FAAHCNR1CNR2 | |
| SCHEMBL4969451 | 0.80 | EPHX2 (0.57) | EPHX2FAAHCNR1CNR2 | |
| SCHEMBL27574988 | 0.79 | EPHX2 (0.53) | EPHX2FAAHLTB4R2HDAC3HDAC4 | |
| SCHEMBL30525093 | 0.77 | EPHX2 (0.73) | EPHX2FAAHCNR1CNR2HTT | |
| SCHEMBL225174 | 0.77 | EPHX2 (0.73) | EPHX2FAAHCNR1CNR2HTT | |
| SCHEMBL27574919 | 0.75 | EPHX2 (0.51) | EPHX2FAAHLTB4R2SOAT1CNR1 | |
| Cinnamic Acid SCHEMBL28752126 | 0.74 | HDAC3 (0.70) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7969707 | 0.74 | TUBB4A (0.71) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7969700 | 0.74 | TUBB4A (0.71) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6252487 | 0.72 | TSHR (0.50) | EPHX2FAAHLTB4R2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101296897-A | PPAR-modulating biaromatic compounds | GALDERMA RES & DEV (FR) | 2008-10-29 | — | — | CN | disclosed |