Oxirane

Oxirane

SCHEMBL27720207

C1CO1.CC(C)c1ccc(O)cc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.54
ESR2 Q92731 5/20 0.54
PDCD1 Q15116 1/20 0.54
CD274 Q9NZQ7 1/20 0.54
TYR P14679 1/20 0.45
PTGS1 P23219 2/20 0.43
LMNA P02545 1/20 0.43
CYP1A2 P05177 1/20 0.43
PGR P06401 1/20 0.43
CHRM2 P08172 1/20 0.43
CYP3A4 P08684 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
AR P10275 1/20 0.43
CYP2D6 P10635 1/20 0.43
MAPT P10636 1/20 0.43
CHRM1 P11229 1/20 0.43
CYP2C9 P11712 1/20 0.43
ALOX15 P16050 1/20 0.43
DRD1 P21728 1/20 0.43
TBXA2R P21731 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroquinone SCHEMBL9580215 0.87 ESR1 (0.68) ESR1ESR2PDCD1CD274TYR
SCHEMBL28954 0.87 ESR1 (0.68) ESR1ESR2PDCD1CD274TYR
SCHEMBL27568003 0.85 ESR1 (0.65) ESR1ESR2PDCD1CD274TYR
SCHEMBL28800543 0.85 ESR1 (0.65) ESR1ESR2PDCD1CD274TYR
SCHEMBL27525142 0.85 ESR1 (0.65) ESR1ESR2PDCD1CD274TYR
SCHEMBL29133983 0.85 ESR1 (0.65) ESR1ESR2PDCD1CD274TYR
SCHEMBL30171502 0.85 ESR1 (0.65) ESR1ESR2PDCD1CD274TYR
SCHEMBL28657617 0.85 ESR1 (0.65) ESR1ESR2PDCD1CD274TYR
Hydrogen Sulfide SCHEMBL27992656 0.85 ESR1 (0.65) ESR1ESR2PDCD1CD274TYR
Benzene SCHEMBL1602387 0.82 ESR1 (0.62) ESR1ESR2PDCD1CD274TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102516893-B Adherent composition and method of temporarily fixing member therewith DENKI KAGAKU KOGYO KK 2014-03-12 CN disclosed
CN-101146837-B Adhesive composition and method for temporarily fixing member using same DENKI KAGAKU KOGYO KK 2012-06-27 CN disclosed
CN-102516893-A Adherent composition and method of temporarily fixing member therewith DENKI KAGAKU KOGYO KK 2012-06-27 CN disclosed
CN-101146837-A Adhesive composition and method for temporarily fixing member using same DENKI KAGAKU KOGYO KK (JP) 2008-03-19 CN disclosed