SCHEMBL27720245

SCHEMBL27720245

N#Cc1cc2c(cc1[N+](=O)[O-])=NC(=O)C(=O)N=2.c1ccc2c(c1)ccc1c3c(ccc12)CCCC3

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 1/20 0.41
GRIA1 P42261 2/20 0.35
GRIA2 P42262 2/20 0.35
GRIA3 P42263 2/20 0.35
GRIA4 P48058 2/20 0.35
GRM6 O15303 1/20 0.35
MAPT P10636 3/20 0.34
TDP1 Q9NUW8 3/20 0.34
POLB P06746 1/20 0.34
CYP2C9 P11712 1/20 0.34
HPGD P15428 1/20 0.34
APEX1 P27695 1/20 0.34
BLM P54132 1/20 0.34
PNMT P11086 1/20 0.34
ALDH1A1 P00352 5/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP1A2 P05177 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL159009 0.75 MAPT (0.53) GRIA1GRIA2GRIA3GRIA4GRM6
Nitrobenzene SCHEMBL27257265 0.74 HPRT1 (0.47) HPRT1PNMTALDH1A1KDM4EMEN1
Nitromethane SCHEMBL28233660 0.74 HPRT1 (0.45) HPRT1MAPTPNMTALDH1A1MEN1
Nitric Acid SCHEMBL27829878 0.74 HPRT1 (0.45) HPRT1MAPTPNMTALDH1A1MEN1
SCHEMBL30456072 0.73 MAPT (0.51) GRIA1GRIA2GRIA3GRIA4GRM6
Water SCHEMBL30261034 0.73 MAPT (0.51) GRIA1GRIA2GRIA3GRIA4GRM6
SCHEMBL626564 0.73 MAPT (0.51) GRIA1GRIA2GRIA3GRIA4GRM6
SCHEMBL27795577 0.73 PNMT (0.49) HPRT1MAPTTDP1PNMTALDH1A1
Water SCHEMBL28388195 0.72 HPRT1 (0.52) HPRT1MAPTTDP1ALDH1A1CYP1A2
Water SCHEMBL27524235 0.72 HPRT1 (0.52) HPRT1MAPTTDP1ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101163481-A Improved gacyclidine formulations NEUROSYSTEC CORP (US) 2008-04-16 CN disclosed