Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16109065 | 1.00 | EPHX1 (0.47) | EPHX1ALDH1A1POLBRECQLSMN1; SMN2 | |
| SCHEMBL1473973 | 0.87 | — | — | |
| SCHEMBL2257067 | 0.77 | — | — | |
| SCHEMBL1475935 | 0.77 | — | — | |
| SCHEMBL348519 | 0.76 | EPHX1 (0.47) | EPHX1ALDH1A1POLBRECQLSMN1; SMN2 | |
| SCHEMBL3623543 | 0.76 | EPHX1 (0.57) | EPHX1ALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL28310343 | 0.76 | EPHX1 (0.57) | EPHX1ALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL19033004 | 0.76 | EPHX1 (0.47) | EPHX1ALDH1A1POLBRECQLSMN1; SMN2 | |
| SCHEMBL1605352 | 0.75 | ALDH1A1 (0.64) | EPHX1ALDH1A1POLBSMN1; SMN2RAB9A | |
| SCHEMBL1605115 | 0.75 | ALDH1A1 (0.64) | EPHX1ALDH1A1POLBSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101166734-A | Novel aminopyridine compounds having Syk inhibitory activity | JAPAN TOBACCO INC (JP) | 2008-04-23 | — | — | CN | disclosed |