Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 14/20 | 0.47 |
| ▸ | CDK4 | P11802 | 10/20 | 0.47 |
| ▸ | CDK9 | P50750 | 9/20 | 0.47 |
| ▸ | AURKA | O14965 | 6/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.47 |
| ▸ | CDK1 | P06493 | 6/20 | 0.43 |
| ▸ | CDK7 | P50613 | 5/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.43 |
| ▸ | CCNH | P51946 | 2/20 | 0.43 |
| ▸ | TNK2 | Q07912 | 4/20 | 0.43 |
| ▸ | WEE1 | P30291 | 3/20 | 0.43 |
| ▸ | FLT3 | P36888 | 3/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27720314 | 0.87 | CDK2 (0.57) | CDK2CDK4CDK9AURKAAURKB | |
| SCHEMBL27741376 | 0.84 | CDK2 (0.59) | CDK2CDK4CDK9AURKAAURKB | |
| SCHEMBL2284017 | 0.83 | CDK2 (0.62) | CDK2CDK4CDK9AURKAAURKB | |
| SCHEMBL27741378 | 0.83 | CDK4 (0.55) | CDK2CDK4CDK9AURKAAURKB | |
| SCHEMBL2286333 | 0.82 | CDK2 (0.64) | CDK2CDK4CDK9AURKAAURKB | |
| SCHEMBL27741373 | 0.81 | CDK2 (0.51) | CDK2CDK4CDK9AURKAAURKB | |
| SCHEMBL27720286 | 0.81 | PAK4 (0.55) | CDK2CDK4CDK9AURKAAURKB | |
| SCHEMBL2289127 | 0.81 | CDK2 (0.51) | CDK2CDK4CDK9AURKAAURKB | |
| SCHEMBL27720301 | 0.80 | CDK2 (0.49) | CDK2CDK4CDK9AURKAAURKB | |
| SCHEMBL2283561 | 0.80 | CDK2 (0.50) | CDK2CDK4CDK9AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101309586-A | Thiazole compounds as fungicides | BAYER CROPSCIENCE AG (DE) | 2008-11-19 | — | — | CN | disclosed |