Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.77 |
| ▸ | MEN1 | O00255 | 5/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | HSPB1 | P04792 | 4/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.54 |
| ▸ | TTR | P02766 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11322040 | 0.93 | MEN1 (0.82) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL27732206 | 0.90 | MAPT (0.68) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL28589234 | 0.89 | MAPT (0.75) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL27713527 | 0.88 | ALDH1A1 (0.73) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL5315876 | 0.87 | MAPT (0.73) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL11600913 | 0.87 | MEN1 (0.73) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL29552654 | 0.87 | ALDH1A1 (1.00) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL10537196 | 0.87 | ALDH1A1 (0.73) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL554311 | 0.87 | ALDH1A1 (1.00) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL25518736 | 0.87 | ALDH1A1 (0.73) | MAPTMEN1KMT2AALDH1A1HSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101245011-B | Process for producing 4,4'bis(2,4-dinitrophenoxy) biphenyl | UNIV DONGHUA | 2011-06-08 | — | — | CN | disclosed |
| CN-101293842-B | Method for preparing 4,4'-di(2,4-diaminophenyloxy)biphenyl | UNIV DONGHUA | 2011-04-27 | — | — | CN | disclosed |
| CN-101293842-A | Method for preparing 4,4'-di(2,4-diaminophenyloxy)biphenyl | UNIV DONGHUA (CN) | 2008-10-29 | — | — | CN | disclosed |
| CN-101245011-A | Process for producing 4,4'bis(2,4-dinitrophenoxy) biphenyl | UNIV DONGHUA (CN) | 2008-08-20 | — | — | CN | disclosed |