Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 15/20 | 0.67 |
| ▸ | CDK4 | P11802 | 12/20 | 0.67 |
| ▸ | ABL1 | P00519 | 4/20 | 0.65 |
| ▸ | PRKCA | P17252 | 4/20 | 0.65 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.65 |
| ▸ | EGFR | P00533 | 1/20 | 0.65 |
| ▸ | AURKA | O14965 | 3/20 | 0.56 |
| ▸ | CDK1 | P06493 | 3/20 | 0.56 |
| ▸ | CDK7 | P50613 | 3/20 | 0.56 |
| ▸ | CDK9 | P50750 | 3/20 | 0.56 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.56 |
| ▸ | BCR | P11274 | 3/20 | 0.55 |
| ▸ | PLK1 | P53350 | 3/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2290834 | 0.92 | CDK2 (0.74) | CDK2CDK4ABL1PRKCAPRKCD | |
| SCHEMBL6156440 | 0.90 | CDK2 (0.67) | CDK2CDK4ABL1PRKCAPRKCD | |
| SCHEMBL12278950 | 0.88 | CDK2 (0.51) | CDK2CDK4ABL1PRKCAPRKCD | |
| SCHEMBL4164771 | 0.85 | ZAP70 (0.54) | CDK2CDK4ABL1PRKCAPRKCD | |
| SCHEMBL4176513 | 0.85 | CDK2 (0.60) | CDK2CDK4ABL1EGFRAURKA | |
| SCHEMBL4154433 | 0.85 | ABL1 (0.54) | CDK2CDK4ABL1PRKCAPRKCD | |
| SCHEMBL6363180 | 0.84 | CDK2 (0.71) | CDK2CDK4AURKACDK1CDK7 | |
| SCHEMBL4159124 | 0.84 | ZAP70 (0.72) | CDK2CDK4ABL1PRKCAPRKCD | |
| SCHEMBL4173509 | 0.83 | CDK2 (0.71) | CDK2CDK4ABL1EGFRAURKA | |
| SCHEMBL4164505 | 0.83 | CDK2 (0.58) | CDK2CDK4ABL1EGFRAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101309586-A | Thiazole compounds as fungicides | BAYER CROPSCIENCE AG (DE) | 2008-11-19 | — | — | CN | disclosed |