SCHEMBL4154433

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4159128	0.86	CDK4 (0.56)	ABL1BCRCDK2CDK4SRC
	SCHEMBL27720404	0.85	CDK2 (0.67)	ABL1BCRCDK2CDK4EGFR
	SCHEMBL28765387	0.84	ABL1 (0.50)	ABL1BCRCDK2CDK4SRC
	SCHEMBL4169340	0.84	CDK2 (0.74)	ABL1CDK2CDK4CCNT1CDK1
	SCHEMBL7461095	0.84	ABL1 (0.72)	ABL1BCRSRCEGFRPRKACA
	SCHEMBL2075737	0.83	CDK2 (0.72)	ABL1CDK2CDK4PRKACACCNT1
	SCHEMBL2073975	0.82	CDK2 (0.62)	ABL1CDK2CDK4PRKACACCNT1
	SCHEMBL6156799	0.81	ABL1 (0.73)	ABL1BCRCDK2CDK4SRC
	SCHEMBL12278950	0.80	CDK2 (0.51)	ABL1BCRCDK2CDK4EGFR
	SCHEMBL6156440	0.80	CDK2 (0.67)	ABL1BCRCDK2CDK4EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.