Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 5/20 | 0.48 |
| ▸ | BRAF | P15056 | 2/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27720500 | 0.83 | KMT2A (0.64) | MEN1KMT2AKDRKCNK3KCNK9 | |
| SCHEMBL28772278 | 0.81 | KCNQ3 (0.62) | MEN1KMT2AKCNK3KCNK9KDM4E | |
| SCHEMBL27720393 | 0.81 | MEN1 (0.61) | MEN1KMT2AKCNK3KCNK9POLB | |
| Cyclopropane SCHEMBL27720374 | 0.80 | MEN1 (0.57) | CSF1RKITMEN1KMT2AKCNK3 | |
| SCHEMBL27720400 | 0.79 | BRAF (0.51) | RAF1BRAFCSF1RKITMEN1 | |
| SCHEMBL27699722 | 0.79 | KCNK3 (0.65) | MEN1KMT2AKCNK3KCNK9POLB | |
| SCHEMBL27699808 | 0.76 | KCNK9 (0.62) | CSF1RMEN1KMT2AKCNK3KCNK9 | |
| SCHEMBL27699765 | 0.75 | NR1H4 (0.62) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL27720418 | 0.74 | CSF1R (0.50) | BRAFCSF1RKITMEN1KMT2A | |
| SCHEMBL27720417 | 0.72 | MAPT (0.69) | MEN1KMT2APOLBKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101128454-A | Pyridine carboxamide derivatives for use as anticancer agents | ASTRAZENECA AB (SE) | 2008-02-20 | — | — | CN | disclosed |