Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.57 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.56 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.56 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.56 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.54 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27720393 | 0.96 | MEN1 (0.61) | MEN1KMT2AKCNK3KCNQ3KCNQ2 | |
| Cyclopropane SCHEMBL27699785 | 0.86 | KCNQ3 (0.62) | MEN1KMT2AKCNK3KCNQ3KCNQ2 | |
| SCHEMBL27720433 | 0.84 | MEN1 (0.64) | MEN1KMT2AKCNK3KCNQ3KCNQ2 | |
| SCHEMBL27720500 | 0.84 | KMT2A (0.64) | MEN1KMT2AKCNK3RAB9ANPC1 | |
| SCHEMBL28772278 | 0.82 | KCNQ3 (0.62) | MEN1KMT2AKCNK3KCNQ3KCNQ2 | |
| SCHEMBL27720385 | 0.82 | KCNQ3 (0.67) | MEN1KMT2AKCNK3KCNQ3KCNQ2 | |
| SCHEMBL27720378 | 0.81 | PIK3CA (0.55) | KCNK3KCNQ3KCNQ2KCNQ5KCNE1 | |
| SCHEMBL27720400 | 0.81 | BRAF (0.51) | MEN1KMT2AKCNK3KCNK9POLB | |
| SCHEMBL27699722 | 0.81 | KCNK3 (0.65) | MEN1KMT2AKCNK3KCNQ3KCNQ2 | |
| SCHEMBL27720442 | 0.80 | RAF1 (0.48) | MEN1KMT2AKCNK3KCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101128454-A | Pyridine carboxamide derivatives for use as anticancer agents | ASTRAZENECA AB (SE) | 2008-02-20 | — | — | CN | disclosed |