Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.51 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.51 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 10/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.46 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3389724 | 0.97 | MAPK14 (0.49) | MAPK14MAPK12MAPK13MAPK11TNF | |
| SCHEMBL3390169 | 0.91 | MAPK14 (0.49) | MAPK14MAPK12MAPK13MAPK11TNF | |
| SCHEMBL3415918 | 0.90 | BRAF (0.47) | MAPK14MAPK12MAPK13MAPK11TNF | |
| SCHEMBL3393244 | 0.89 | MAPK14 (0.58) | MAPK14MAPK12MAPK13MAPK11BRAF | |
| SCHEMBL3391154 | 0.89 | MAPK14 (0.47) | MAPK14MAPK12MAPK13MAPK11TNF | |
| SCHEMBL3391094 | 0.87 | KCNJ6 (0.47) | MAPK14MAPK12MAPK13MAPK11TNF | |
| SCHEMBL3390667 | 0.85 | KCNJ6 (0.45) | MAPK14MAPK12MAPK13MAPK11TNF | |
| SCHEMBL27720483 | 0.84 | MAPK14 (0.46) | MAPK14MAPK12MAPK13MAPK11TNF | |
| SCHEMBL3422287 | 0.84 | MAPK14 (0.55) | MAPK14MAPK12MAPK13MAPK11BRAF | |
| SCHEMBL3170571 | 0.84 | MAPK14 (0.60) | MAPK14MAPK12MAPK13MAPK11BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101296922-A | Kinase inhibitors | LILLY CO ELI (US) | 2008-10-29 | — | — | CN | disclosed |