Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 3/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368732 | 0.81 | HRH3 (0.59) | ALDH1A1CYP1A2USP2HSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL15106704 | 0.79 | HRH3 (0.58) | ALDH1A1CYP1A2USP2HSD17B10KDM4E | |
| SCHEMBL7492849 | 0.79 | SUV39H2 (0.40) | CYP2C19ALDH1A1CYP1A2USP2ALOX15 | |
| Hydrochloric Acid SCHEMBL17580670 | 0.79 | HRH3 (0.58) | ALDH1A1CYP1A2USP2HSD17B10KDM4E | |
| SCHEMBL24922177 | 0.79 | KDM4E (0.46) | CYP2C19ALDH1A1CYP1A2MEN1USP2 | |
| SCHEMBL13033968 | 0.78 | KMT2A (0.57) | CYP2C19ALDH1A1CYP1A2MEN1USP2 | |
| SCHEMBL17310231 | 0.77 | LRRK2 (0.62) | CYP2C19ALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL4722662 | 0.77 | SORD (0.50) | CYP2C19ALDH1A1CYP1A2MEN1USP2 | |
| SCHEMBL1311931 | 0.77 | MAPK1 (0.52) | MEN1KMT2AMTORPIK3CASMN1; SMN2 | |
| SCHEMBL5457199 | 0.76 | PIK3CA (0.55) | CYP2C19ALDH1A1CYP1A2MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101305010-A | Raf inhibitor compounds and methods of use thereof | ARRAY BIOPHARMA INC (US) | 2008-11-12 | — | — | CN | disclosed |