Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.55 |
| ▸ | F7 | P08709 | 2/20 | 0.52 |
| ▸ | F3 | P13726 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | PPARA | Q07869 | 5/20 | 0.48 |
| ▸ | TERT | O14746 | 3/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.47 |
| ▸ | TOP1 | P11387 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL193589 | 0.98 | — | — | |
| SCHEMBL3968467 | 0.98 | — | — | |
| SCHEMBL193588 | 0.98 | — | — | |
| SCHEMBL27873374 | 0.95 | PTPN1 (0.55) | PTPN1F7F3PPARGPPARA | |
| Hydrochloric Acid SCHEMBL10893640 | 0.95 | PTPN1 (0.55) | PTPN1F7F3PPARGPPARA | |
| Acetic Acid SCHEMBL27818848 | 0.93 | PTPN1 (0.58) | PTPN1F7F3PPARGPPARA | |
| SCHEMBL21820812 | 0.93 | PTPN1 (0.62) | PTPN1F7F3PPARGPPARA | |
| SCHEMBL21820811 | 0.93 | PTPN1 (0.62) | PTPN1F7F3PPARGPPARA | |
| SCHEMBL9130191 | 0.91 | F7 (0.64) | PTPN1F7F3PPARGPPARA | |
| Cyclopentane SCHEMBL1045041 | 0.91 | PTPN1 (0.51) | PTPN1F7F3PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101307015-A | Process for preparing cilastatin sodium | SHENZHEN HAIBIN PHARMACEUTICAL (CN) | 2008-11-19 | — | — | CN | claimed |
| CN-115108934-B | Preparation method of cilastatin intermediate sodium | 珠海联邦制药股份有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-115108934-A | Preparation method of cilastatin intermediate sodium | 珠海联邦制药股份有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-101307015-A | Process for preparing cilastatin sodium | SHENZHEN HAIBIN PHARMACEUTICAL (CN) | 2008-11-19 | — | — | CN | disclosed |