Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | F3 | P13726 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | TERT | O14746 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopentane SCHEMBL1045042 | 1.00 | PTPN1 (0.51) | PTPN1F7F3PPARGPPARA | |
| SCHEMBL193589 | 0.93 | — | — | |
| SCHEMBL3968467 | 0.93 | — | — | |
| SCHEMBL193588 | 0.93 | — | — | |
| SCHEMBL27720771 | 0.91 | PTPN1 (0.55) | PTPN1F7F3PPARGPPARA | |
| Hydrochloric Acid SCHEMBL10893640 | 0.91 | PTPN1 (0.55) | PTPN1F7F3PPARGPPARA | |
| SCHEMBL27873374 | 0.91 | PTPN1 (0.55) | PTPN1F7F3PPARGPPARA | |
| SCHEMBL21820812 | 0.89 | PTPN1 (0.62) | PTPN1F7F3PPARGPPARA | |
| SCHEMBL21820811 | 0.89 | PTPN1 (0.62) | PTPN1F7F3PPARGPPARA | |
| Acetic Acid SCHEMBL27818848 | 0.89 | PTPN1 (0.58) | PTPN1F7F3PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227672-A1 | NON-ACIDIC CYCLOPENTANE HEPTANOIC ACID, 2-CYCLOALKYL OR ARYLALKYL DERIVATIVES AS THERAPEUTIC AGENTS | WOODWARD DAVID F | 2009-09-10 | — | — | US | claimed |
| US-20030114528-A1 | Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents | ALLERGAN, INC. | 2003-06-19 | — | — | US | claimed |
| EP-0915704-A1 | USE OF PHOSPHINYLOXYALKYL AND PHOSPHONAMIDOALKYL DERIVATIVES OF CYCLOPENTANE(ENE) AS THERAPEUTIC AGENTS | Vision Pharmaceuticals L.P. (US) | 1999-05-19 | — | — | EP | claimed |
| WO-1997037666-A1 | USE OF PHOSPHINYLOXYALKYL AND PHOSPHONAMIDOALKYL DERIVATIVES OF CYCLOPENTANE(ENE) AS THERAPEUTIC AGENTS | ALLERGAN SALES, INC. (US) | 1997-10-16 | — | — | WO | claimed |
| US-5658897-A | MUSCLE RELAXANTS AND OCULAR HYPOTENSIVE AGENTS | ALLERGAN (US) | 1997-08-19 | — | — | US | claimed |
| EP-0714303-A1 | CYCLOPENTANE(ENE) HEPTANOIC OR CYCLOPENTANE(ENE) HEPTENOIC ACID, 2-HYDROCARBYL SULFONAMIDOMETHYL AND DERIVATIVES THEREOF AS THERAPEUTIC AGENTS | ALLERGAN, INC. (US) | 1996-06-05 | — | — | EP | claimed |
| US-5457131-A | Ocular hypotensive agents | ALLERGAN, INC. (US) | 1995-10-10 | — | — | US | claimed |
| WO-1995005178-A1 | CYCLOPENTANE(ENE) HEPTANOIC OR CYCLOPENTANE(ENE) HEPTENOIC ACID, 2-HYDROCARBYL SULFONAMIDOMETHYL AND DERIVATIVES THEREOF AS THERAPEUTIC AGENTS | ALLERGAN, INC. (US) | 1995-02-23 | — | — | WO | claimed |
| US-5387608-A | Ocular hypotensive agents for treatment of glaucoma; smooth muscle relaxants | ALLERGAN, INC. (US) | 1995-02-07 | — | — | US | claimed |
| US-5332730-A | Ocular hypotensive | ALLERGAN, INC. (US) | 1994-07-26 | — | — | US | claimed |
| WO-1994008586-A2 | AZIDO DERIVATIVES OF CYCLOPENTANE HEPTANOIC OR HEPTENOIC ACID | ALLERGAN, INC. (US) | 1994-04-28 | — | — | WO | claimed |
| US-20210299023-A1 | COMPOSITIONS AND METHODS FOR HAIR GROWTH | ALLERGAN INC (US) | 2021-09-30 | — | — | US | disclosed |
| EP-2640350-B1 | COMPOSITIONS AND METHODS FOR HAIR GROWTH | YOELIN STEVEN (US) | 2018-09-26 | — | — | EP | disclosed |
| US-20170112853-A1 | Hypotensive Lipid And Timolol Compositions And Methods Of Using Same | ALLERGAN INC (US) | 2017-04-27 | — | — | US | disclosed |
| US-9474760-B2 | Hypotensive lipid and timolol compositions and methods of using same | ALLERGAN, INC. (US) | 2016-10-25 | — | — | US | disclosed |
| US-5352708-A | For treating glaucoma | ALLERGAN, INC. (US) | 1994-10-04 | — | — | US | disclosed |
| US-5332730-A | Ocular hypotensive | ALLERGAN, INC. (US) | 1994-07-26 | — | — | US | disclosed |
| WO-1994008586-A2 | AZIDO DERIVATIVES OF CYCLOPENTANE HEPTANOIC OR HEPTENOIC ACID | ALLERGAN, INC. (US) | 1994-04-28 | — | — | WO | disclosed |
| WO-1994006433-A1 | NON-ACIDIC CYCLOPENTANE HEPTANOIC ACID, 2-CYCLOALKYL OR ARYLALKYL DERIVATIVES AS THERAPEUTIC AGENTS | ALLERGAN, INC. (US) | 1994-03-31 | — | — | WO | disclosed |
| US-3953470-A | Substituted prostaglandin derivatives | SYNTEX (U.S.A.) INC. (US) | 1976-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210299023-A1 | COMPOSITIONS AND METHODS FOR HAIR GROWTH | CYP21A2, CYP2A7, PPP3R1 | PTPN1 978/4885F7 2237/4885F3 2509/4885 |
| US-20090227672-A1 | NON-ACIDIC CYCLOPENTANE HEPTANOIC ACID, 2-CYCLOALKYL OR ARYLALKYL DERIVATIVES AS THERAPEUTIC AGENTS | AGTR2, MYOC, PTGIR | PTPN1 1191/4885F7 2088/4885F3 2062/4885 |
| US-20170112853-A1 | Hypotensive Lipid And Timolol Compositions And Methods Of Using Same | APOB, HDLBP, LIPC | PTPN1 2908/4885F7 1446/4885F3 2112/4885 |
| US-20030114528-A1 | Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents | AGTR2, MYOC, PTGIR | PTPN1 1191/4885F7 2088/4885F3 2062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.