Benzamide

Benzamide

SCHEMBL27722018

NC(=O)c1ccccc1.O=C(O)c1cc2ccccc2cc1O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
PARP1 P09874 2/20 0.55
POLB P06746 2/20 0.55
CYP3A4 P08684 1/20 0.55
TSHR P16473 1/20 0.55
CYP2C19 P33261 1/20 0.55
RECQL P46063 1/20 0.55
BLM P54132 1/20 0.55
PMP22 Q01453 1/20 0.55
HSD17B10 Q99714 1/20 0.55
IDO1 P14902 1/20 0.53
KMT2A Q03164 3/20 0.53
MEN1 O00255 2/20 0.53
GRIN2D O15399 1/20 0.53
GRIN2A Q12879 1/20 0.53
GRIN2B Q13224 1/20 0.53
GRIN2C Q14957 1/20 0.53
MITF O75030 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10422377 0.89 NR4A1 (0.47) MAPTTDP1L3MBTL1POLBIDO1
Hydrazine SCHEMBL28242022 0.87 IDO1 (0.62) MAPTTDP1CYP3A4CYP2C19RECQL
SCHEMBL6460 0.87 GRIN2D (0.66) MAPTTDP1IDO1KMT2AMEN1
SCHEMBL29358330 0.87 GRIN2D (0.66) MAPTTDP1IDO1KMT2AMEN1
Acetamide SCHEMBL10951863 0.86 IDO1 (0.56) MAPTTDP1POLBIDO1KMT2A
Hydrochloric Acid SCHEMBL28419671 0.86 IDO1 (0.56) MAPTTDP1IDO1KMT2AMEN1
SCHEMBL9017415 0.85 GRIN2D (0.63) MAPTTDP1POLBIDO1KMT2A
SCHEMBL5964696 0.85 GRIN2D (0.63) MAPTTDP1POLBIDO1KMT2A
SCHEMBL8411324 0.85 GRIN2D (0.63) MAPTTDP1TSHRIDO1KMT2A
SCHEMBL10800188 0.85 GRIN2D (0.63) MAPTTDP1POLBIDO1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101313035-B Naphthol AS colorants and their use AGFA GRAPHICS NV 2012-12-05 CN disclosed
CN-101313034-B Non-aqueous dispersions of naphthol AS pigments AGFA GRAPHICS NV 2012-09-05 CN disclosed
CN-101313035-A Naphthol AS colorants and their use AGFA GRAPHICS NV (BE) 2008-11-26 CN disclosed
CN-101313034-A Non-aqueous dispersions of naphthol AS pigments AGFA GRAPHICS NV (BE) 2008-11-26 CN disclosed