Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | BAD | Q92934 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.37 |
| ▸ | IL1RN | P18510 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | F9 | P00740 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28118478 | 0.86 | KIF11 (0.45) | KIF11PRCPBCL2L1BADBCHE | |
| SCHEMBL27479459 | 0.83 | KIF11 (0.46) | KIF11BCL2L1BADTSHR | |
| SCHEMBL27343325 | 0.83 | KIF11 (0.45) | KIF11BCL2L1BADBCHEHTR1A | |
| Biphenyl SCHEMBL27766630 | 0.81 | KIF11 (0.47) | KIF11TSHR | |
| SCHEMBL28840503 | 0.81 | KIF11 (0.47) | KIF11BCL2L1BADTSHRCDK4 | |
| Anthracene SCHEMBL28161569 | 0.81 | KIF11 (0.41) | KIF11BCHECDK4CCND1 | |
| SCHEMBL28159978 | 0.81 | KIF11 (0.42) | KIF11BCL2L1BADBCHETSHR | |
| SCHEMBL11023731 | 0.80 | PRCP (0.58) | PRCPBCL2L1BADANPEPIL1RN | |
| SCHEMBL30285902 | 0.80 | PRCP (0.58) | PRCPBCL2L1BADANPEPIL1RN | |
| Benzene SCHEMBL27260397 | 0.79 | HPRT1 (0.52) | KIF11TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101180290-A | Hydogrenated benzo[c] thiophene derivatives as immunomodulators | ACTELION PHARMACEUTICALS LTD (CH) | 2008-05-14 | — | — | CN | disclosed |