Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 12/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27701072 | 0.90 | TDP1 (0.43) | TDP1ITGB3ITGA2BNAMPTGNAI3 | |
| Tert-Butyl Formate SCHEMBL27591602 | 0.87 | TDP1 (0.46) | TDP1ITGB3ITGA2BGNAI3GNAO1 | |
| Tert-Butyl Formate SCHEMBL27722913 | 0.87 | TDP1 (0.50) | TDP1ITGB3ITGA2BNAMPTGNAI3 | |
| Tert-Butyl Formate SCHEMBL27702406 | 0.85 | TDP1 (0.48) | TDP1ITGB3ITGA2BGNAI3GNAO1 | |
| Tert-Butyl Formate SCHEMBL27779744 | 0.84 | TDP1 (0.41) | TDP1ITGB3ITGA2BNAMPTTPSAB1 | |
| Tert-Butyl Formate SCHEMBL27742718 | 0.84 | TDP1 (0.41) | TDP1ITGB3ITGA2BNAMPTTPSAB1 | |
| Tert-Butyl Formate SCHEMBL27574820 | 0.84 | TDP1 (0.41) | TDP1ITGB3ITGA2BNAMPTTPSAB1 | |
| Tert-Butyl Formate SCHEMBL28759827 | 0.84 | KMT2A (0.39) | TDP1SLC6A4 | |
| Tert-Butyl Formate SCHEMBL27851598 | 0.83 | SLC6A1 (0.43) | TDP1ITGB3ITGA2BGNAI3GNAO1 | |
| Tert-Butyl Formate SCHEMBL27784291 | 0.83 | SLC6A1 (0.43) | TDP1ITGB3ITGA2BGNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103391936-B | Carcinostatic agent | THE UNIVERSITY OF TOKYO (JP) | 2016-04-27 | — | — | CN | disclosed |
| CN-103391936-A | Anticancer agent | NAT UNIV CORP UNIV TOKYO | 2013-11-13 | — | — | CN | disclosed |
| CN-101160287-B | Pyridyl non-aromatic nitrogenated heterocyclic-1-carboxylate ester derivative | ASTELLAS PHARMA INC | 2011-08-03 | — | — | CN | disclosed |
| CN-102131778-A | Heterocyclic gpcr agonists | PROSIDION LTD | 2011-07-20 | — | — | CN | disclosed |
| CN-102007126-A | Compounds and compositions as modulators of gpr119 activity | IRM LLC | 2011-04-06 | — | — | CN | disclosed |
| CN-101528680-A | New phenylsulfamoyl benzamide derivatives as bradykinin antagonists | RICHTER GEDEON NYRT (HU) | 2009-09-09 | — | — | CN | disclosed |
| CN-101160287-A | Pyridyl non-aromatic nitrogenated heterocyclic-1-carboxylate ester derivative | ASTELLAS PHARMA INC (JP) | 2008-04-09 | — | — | CN | disclosed |