SCHEMBL27723136

SCHEMBL27723136

C=C[C@@]1(NCc2ccccc2C)C=CC=CC1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.36
GAA P10253 2/20 0.36
CHRM2 P08172 1/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
ALDH1A1 P00352 5/20 0.33
HPGD P15428 3/20 0.33
MEN1 O00255 2/20 0.31
PKM P14618 1/20 0.31
HTT P42858 2/20 0.31
CYP2A13 Q16696 1/20 0.31
CXCR4 P61073 1/20 0.30
LMNA P02545 2/20 0.30
KDM4E B2RXH2 1/20 0.30
ACHE P22303 1/20 0.30
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27702755 0.86 HDAC4 (0.31)
SCHEMBL27723128 0.83 TACR1 (0.42) KMT2AGAACHRM2ALDH1A1MEN1
SCHEMBL27500634 0.80 SMN1; SMN2 (0.33) KMT2AALDH1A1MEN1HTTLMNA
SCHEMBL27723127 0.80 SMN1; SMN2 (0.33) KMT2AALDH1A1MEN1HTTLMNA
SCHEMBL7704410 0.70
SCHEMBL21311750 0.67 CHRM2 (0.48) KMT2AGAACHRM2NPC1RAB9A
SCHEMBL27702721 0.67
SCHEMBL28793599 0.67
SCHEMBL3763912 0.67 ZDHHC20 (0.30)
SCHEMBL28045483 0.67 ZDHHC20 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101166708-B Preparation method of optically active 3-methylcyclopentadecanone and intermediate thereof TAKASAGO PERFUMERY CO LTD 2011-11-23 CN disclosed
CN-101166708-A Preparation method of optically active 3-methylcyclopentadecanone and intermediate thereof TAKASAGO PERFUMERY CO LTD (JP) 2008-04-23 CN disclosed