Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2865610 | 0.81 | CA12 (0.47) | MEN1GAAKMT2AHPGDLMNA | |
| SCHEMBL2858060 | 0.80 | CA1 (0.59) | MEN1GAAKMT2AHPGDALDH1A1 | |
| SCHEMBL2862880 | 0.80 | CA1 (0.59) | MEN1GAAKMT2AHPGDALDH1A1 | |
| SCHEMBL2854148 | 0.78 | HPGD (0.43) | MEN1GAAKMT2AHPGDALDH1A1 | |
| SCHEMBL27744297 | 0.77 | POLB (0.42) | KMT2AANPEPNPC1POLBRAB9A | |
| SCHEMBL2849738 | 0.77 | HPGD (0.46) | MEN1GAAKMT2AHPGDLMNA | |
| SCHEMBL12799314 | 0.75 | CTSS (0.58) | HPGDANPEPPOLBTSHR | |
| SCHEMBL14471184 | 0.75 | HPGD (0.59) | MEN1GAAKMT2AHPGDLMNA | |
| SCHEMBL2863206 | 0.71 | KMT2A (0.50) | MEN1GAAKMT2ALMNAALDH1A1 | |
| SCHEMBL2855929 | 0.70 | CA12 (0.59) | MEN1KMT2AMAPTANPEPTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101282940-B | Fluorine-containing compound | NPS PHARMA INC | 2013-02-13 | — | — | CN | claimed |
| CN-101282940-A | Fluorine-containing compound | NPS PHARMA INC (US) | 2008-10-08 | — | — | CN | claimed |