Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.43 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | ACACA | Q13085 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27665041 | 0.90 | DPP4 (0.43) | DPP4DPP9DPP8ACACBACACA | |
| SCHEMBL5240240 | 0.90 | DPP4 (0.48) | DPP4DPP9DPP8GRM2CYP1A2 | |
| SCHEMBL27702867 | 0.88 | DPP4 (0.55) | DPP4DPP9DPP8 | |
| SCHEMBL27702869 | 0.84 | DPP4 (0.40) | DPP4DPP9DPP8ACACBACACA | |
| SCHEMBL5241529 | 0.80 | DPP4 (0.46) | DPP4DPP9DPP8GRM2CYP1A2 | |
| SCHEMBL5239762 | 0.80 | DPP4 (0.67) | DPP4DPP9DPP8 | |
| SCHEMBL27643612 | 0.79 | DPP4 (0.44) | DPP4DPP9DPP8 | |
| Hydrochloric Acid SCHEMBL5242996 | 0.79 | DPP4 (0.69) | DPP4DPP9DPP8 | |
| Hydrochloric Acid SCHEMBL27664869 | 0.76 | DPP4 (0.57) | DPP4DPP9DPP8 | |
| SCHEMBL5449935 | 0.75 | DPP4 (0.55) | DPP4DPP9DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101166725-A | Pyridylacetic acid compound | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2008-04-23 | — | — | CN | disclosed |