Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.48 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5241529 | 0.90 | DPP4 (0.46) | DPP4DPP9DPP8KDM4AMAPT | |
| SCHEMBL27723360 | 0.90 | DPP4 (0.43) | DPP4DPP9DPP8GRM2CYP1A2 | |
| SCHEMBL4112465 | 0.85 | DPP4 (0.68) | DPP4DPP9DPP8 | |
| SCHEMBL5239762 | 0.84 | DPP4 (0.67) | DPP4DPP9DPP8 | |
| SCHEMBL5240472 | 0.83 | DPP4 (0.43) | DPP4DPP9DPP8 | |
| Hydrochloric Acid SCHEMBL5242996 | 0.83 | DPP4 (0.69) | DPP4DPP9DPP8 | |
| SCHEMBL4117782 | 0.81 | DPP4 (0.49) | DPP4DPP9DPP8CCNCCDK8 | |
| SCHEMBL27665041 | 0.81 | DPP4 (0.43) | DPP4DPP9DPP8GRM2CYP1A2 | |
| SCHEMBL5451905 | 0.81 | DPP4 (0.48) | DPP4DPP9DPP8KDM4A | |
| SCHEMBL5739223 | 0.80 | DPP4 (0.44) | DPP4DPP9DPP8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1851202-A1 | PYRIDYL ACETIC ACID COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006090915-A1 | PYRIDYL ACETIC ACID COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-08-31 | — | — | WO | disclosed |