Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27703383 | 0.85 | CNR1 (0.39) | NPSR1CNR1CDK8CLK4GAA | |
| SCHEMBL27723968 | 0.80 | EPHX2 (0.37) | CNR1GAALMNAMEN1KMT2A | |
| SCHEMBL4592614 | 0.79 | MAPT (0.38) | NPSR1GAALMNAMEN1KMT2A | |
| SCHEMBL27703395 | 0.78 | CNR1 (0.42) | CNR1LMNAALDH1A1 | |
| SCHEMBL27703382 | 0.78 | MAPT (0.31) | NPSR1CNR1MAPT | |
| SCHEMBL4591787 | 0.78 | QPCT (0.47) | NPSR1CNR1GAALMNAMEN1 | |
| SCHEMBL4592356 | 0.77 | EPHX2 (0.34) | CNR1GAAALDH1A1 | |
| SCHEMBL27703386 | 0.77 | CYP3A4 (0.38) | CNR1GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL4593111 | 0.77 | QPCT (0.37) | NPSR1GAALMNAMEN1KMT2A | |
| SCHEMBL27703435 | 0.77 | CHRM5 (0.36) | CNR1MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101189209-A | C5a receptor antagonists | JERINI AG (DE) | 2008-05-28 | — | — | CN | claimed |
| CN-101189209-A | C5a receptor antagonists | JERINI AG (DE) | 2008-05-28 | — | — | CN | disclosed |