Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28969842 | 0.83 | CYSLTR2 (0.55) | PPARGPPARACYSLTR2CYSLTR1 | |
| SCHEMBL27473189 | 0.81 | DPP4 (0.41) | CYSLTR2CYSLTR1KDM4ECYP1A2TSHR | |
| SCHEMBL5322911 | 0.81 | MAPT (0.41) | PPARGPPARAPOLBKDM4EALDH1A1 | |
| SCHEMBL19951679 | 0.80 | PPARG (0.39) | PPARGPPARAPOLBKDM4EALDH1A1 | |
| SCHEMBL1162115 | 0.80 | PPARG (0.39) | PPARGPPARAPOLBKDM4EALDH1A1 | |
| SCHEMBL28306686 | 0.80 | CYP1A2 (0.54) | POLBKDM4EALDH1A1HSD17B10CYP1A2 | |
| Methane SCHEMBL28344019 | 0.79 | PPARG (0.38) | PPARGPPARAPOLBKDM4EALDH1A1 | |
| SCHEMBL6262528 | 0.78 | ACP3 (0.41) | PPARGPPARAPOLBKDM4EALDH1A1 | |
| SCHEMBL8425190 | 0.78 | ALDH1A1 (0.38) | CYSLTR2CYSLTR1POLBKDM4EALDH1A1 | |
| SCHEMBL22383428 | 0.78 | TSHR (0.48) | PPARGPPARAPOLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102746214-A | Novel indoline compounds | FOURNIER LAB SA | 2012-10-24 | — | — | CN | disclosed |
| CN-101184731-A | Indoline compounds | FOURNIER LAB SA (FR) | 2008-05-21 | — | — | CN | disclosed |