Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MYOC | Q99972 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 3/20 | 0.46 |
| ▸ | PYGM | P11217 | 3/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.45 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.45 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28335276 | 0.87 | MEN1 (0.50) | MEN1KMT2AKDM4ESRD5A2MCL1 | |
| SCHEMBL3639473 | 0.86 | KDM4E (0.52) | KDM4EMCL1MAPTALDH1A1PYGL | |
| SCHEMBL27668680 | 0.84 | KDM4E (0.54) | MEN1KMT2AKDM4ESRD5A2MCL1 | |
| SCHEMBL13648145 | 0.84 | KDR (0.61) | MEN1KMT2AMAPK1 | |
| SCHEMBL4373826 | 0.82 | AURKB (0.43) | MEN1KMT2AKDM4EMCL1MAPT | |
| SCHEMBL3551485 | 0.82 | KDM4E (0.45) | MEN1KMT2AKDM4ESRD5A2MCL1 | |
| SCHEMBL28329712 | 0.82 | GAA (0.53) | MEN1KMT2AKDM4ERAB9AMAPT | |
| SCHEMBL27668740 | 0.82 | PYGL (0.51) | MEN1KMT2AKDM4EMAPTMAPK1 | |
| SCHEMBL858556 | 0.81 | PYGL (0.42) | MEN1KMT2AKDM4EMCL1MAPT | |
| SCHEMBL15221593 | 0.81 | TSHR (0.50) | MEN1KMT2AKDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642837-B | Pyridine amide compound containing triazole or quinolinone structure and application thereof | 江西科技师范大学 | 2023-03-21 | — | — | CN | disclosed |
| CN-110642837-A | Pyridine amide compound containing triazole or quinolinone structure and application thereof | 江西科技师范大学 | 2020-01-03 | — | — | CN | disclosed |
| CN-110563697-A | preparation and application of 2-pyridine carboxamide compound | 江西科技师范大学 | 2019-12-13 | — | — | CN | disclosed |
| CN-101198590-B | pyridine derivative and pyrimidine derivative (3) | EISAI R&D MAN CO LTD | 2012-05-09 | — | — | CN | disclosed |
| CN-101198590-A | Novel pyridine derivative and pyrimidine derivative (3) | EISAI R&D MAN CO LTD (JP) | 2008-06-11 | — | — | CN | disclosed |