Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.44 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | F13A1 | P00488 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27282340 | 0.89 | ALOX5 (0.43) | POLBMAPK1SMN1; SMN2ALOX5 | |
| SCHEMBL11000559 | 0.84 | POLB (0.50) | POLBMAPK1SMN1; SMN2ALOX5IMPDH1 | |
| SCHEMBL11001669 | 0.84 | POLB (0.50) | POLBMAPK1SMN1; SMN2ALOX5IMPDH1 | |
| SCHEMBL7327155 | 0.84 | POLB (0.50) | POLBMAPK1SMN1; SMN2ALOX5IMPDH1 | |
| SCHEMBL7324262 | 0.84 | POLB (0.50) | POLBMAPK1SMN1; SMN2ALOX5IMPDH1 | |
| SCHEMBL27281800 | 0.83 | ALOX5 (0.47) | ALOX5 | |
| SCHEMBL11000696 | 0.81 | POLB (0.47) | POLBMAPK1SMN1; SMN2ALOX5IMPDH1 | |
| SCHEMBL11001924 | 0.81 | POLB (0.47) | POLBMAPK1SMN1; SMN2ALOX5IMPDH1 | |
| SCHEMBL7320031 | 0.79 | POLB (0.46) | POLBMAPK1SMN1; SMN2ALOX5IMPDH1 | |
| SCHEMBL7320313 | 0.73 | ALOX5 (0.47) | POLBMAPK1SMN1; SMN2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101333158-B | Method for preparing idebenone | Suzhou lixin pharmaceutical co ltd | 2010-07-21 | — | — | CN | disclosed |
| CN-101333158-A | Method for preparing idebenone | SUZHOU LIXIN PHARMACEUTICAL CO (CN) | 2008-12-31 | — | — | CN | disclosed |