SCHEMBL27725317

SCHEMBL27725317

CC1(C)C2CCC1(CS(=O)(=O)O)CC2.NC(=O)c1ccccc1C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.40
CYP2D6 P10635 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP3A4 P08684 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP1A2 P05177 2/20 0.37
CXCR3 P49682 1/20 0.34
ALOX15 P16050 2/20 0.33
ALDH1A1 P00352 1/20 0.33
DRD2 P14416 1/20 0.33
DRD3 P35462 1/20 0.33
KCNH2 Q12809 1/20 0.33
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
P2RX7 Q99572 1/20 0.32
F2 P00734 3/20 0.32
PRSS1 P07477 3/20 0.32
PRSS2 P07478 3/20 0.32
PRSS3 P35030 3/20 0.32
OPRM1 P35372 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27725321 0.71 ALDH1A1 (0.56) ALOX15ALDH1A1TSHRSMN1; SMN2F2
SCHEMBL25689888 0.70 KMT2A (0.34) CYP2C19CYP2D6CYP2C9CYP1A2CXCR3
Benzene SCHEMBL28074245 0.67 ALDH1A1 (0.74) CYP2C19CYP3A4TDP1ALOX15ALDH1A1
SCHEMBL7477977 0.67 ALDH1A1 (0.74) CYP2C19CYP3A4TDP1ALOX15ALDH1A1
SCHEMBL31390276 0.67 ALDH1A1 (0.74) CYP2C19CYP3A4TDP1ALOX15ALDH1A1
SCHEMBL8771 0.67 ALDH1A1 (0.74) CYP2C19CYP3A4TDP1ALOX15ALDH1A1
Benzene SCHEMBL27461159 0.67 ALDH1A1 (0.74) CYP2C19CYP3A4TDP1ALOX15ALDH1A1
Cyclohexane SCHEMBL29048825 0.66 ALDH1A1 (0.64) CYP2C19CYP3A4TDP1ALOX15ALDH1A1
Ammonia Solution, Strong SCHEMBL4887278 0.66 ALDH1A1 (0.70) CYP2C19CYP3A4TDP1ALOX15ALDH1A1
SCHEMBL28957788 0.66 ALDH1A1 (0.70) CYP2C19CYP3A4TDP1ALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101186678-A Acid-degradable resin compositions containing ketene-aldehyde copolymer NIPPON SODA CO (JP) 2008-05-28 CN disclosed