Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27681131 | 0.82 | CYP1A2 (0.63) | HPRT1CYP1A2HSD17B10HPGDTSHR | |
| SCHEMBL25279300 | 0.82 | HPRT1 (0.56) | HPRT1CYP1A2HSD17B10HPGDTSHR | |
| SCHEMBL27869292 | 0.81 | HPRT1 (0.50) | HPRT1CYP1A2HSD17B10HPGDTSHR | |
| SCHEMBL254544 | 0.81 | CYP1A2 (0.60) | HPRT1CYP1A2HSD17B10HPGDTSHR | |
| SCHEMBL29946590 | 0.81 | CYP1A2 (0.60) | HPRT1CYP1A2HSD17B10HPGDTSHR | |
| SCHEMBL29436081 | 0.80 | CYP1A2 (0.60) | HPRT1CYP1A2HSD17B10HPGDTSHR | |
| SCHEMBL20508159 | 0.80 | CYP1A2 (0.60) | HPRT1CYP1A2HSD17B10HPGDTSHR | |
| SCHEMBL11076291 | 0.80 | HPRT1 (0.58) | HPRT1CYP1A2HSD17B10HPGDTSHR | |
| SCHEMBL30903911 | 0.80 | CYP1A2 (0.60) | HPRT1CYP1A2HSD17B10HPGDTSHR | |
| SCHEMBL27684934 | 0.80 | MAPT (0.46) | HPRT1CYP1A2HSD17B10HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104583224-A | Process for preparing diastereomerically enriched phosphoramidate derivatives of nucleoside compounds for treatment of viral infections | BRISTOL MYERS SQUIBB CO | 2015-04-29 | — | — | CN | disclosed |
| CN-101535299-B | 5-lipoxygenase-activating protein (flap) inhibitors | PANMIRA PHARMACEUTICALS LLC | 2013-09-25 | — | — | CN | disclosed |
| CN-101331117-B | 5-lipoxygenase-activating protein (FLAP) inhibitors | AMIRA PHARMACEUTICALS INC | 2012-09-05 | — | — | CN | disclosed |
| CN-102295637-A | 5-lipoxygenase-activating protein (FLAP) inhibitors | AMIRA PHARMACEUTICALS INC | 2011-12-28 | — | — | CN | disclosed |
| CN-101687791-A | 5-lipoxygenase-activating protein (flap) inhibitors | AMIRA PHARMACEUTICALS INC | 2010-03-31 | — | — | CN | disclosed |
| CN-101535299-A | 5-lipoxygenase-activating protein (FLAP) inhibitors | AMIRA PHARMACEUTICALS INC (US) | 2009-09-16 | — | — | CN | disclosed |
| CN-101331117-A | 5-lipoxygenase-activating protein (FLAP) inhibitors | AMIRA PHARMACEUTICALS INC (US) | 2008-12-24 | — | — | CN | disclosed |
| CN-1438890-A | Adenosine receptor modulators | HOFFMANNLA ROCHE AG F (CH) | 2003-08-27 | — | — | CN | disclosed |