SCHEMBL27725874

SCHEMBL27725874

NCc1ccccc1-c1cccc2c1O[CH]CC2

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PNMT P11086 3/20 0.45
DPP4 P27487 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3787333 0.71 DPP4 (0.73) PNMTDPP4
SCHEMBL1150915 0.66 PARP1 (0.51) PNMT
SCHEMBL10494224 0.65 PNMT (0.71) PNMTDPP4
SCHEMBL28823798 0.65 PNMT (0.47) PNMTDPP4
SCHEMBL14062929 0.64 PARP1 (0.41) PNMT
SCHEMBL3805255 0.63 DPP4 (0.55) PNMTDPP4
SCHEMBL4989872 0.62 PNMT (1.00) PNMTDPP4
SCHEMBL16792809 0.62 PNMT (0.62) PNMTDPP4
SCHEMBL10911429 0.62 PNMT (0.67) PNMTDPP4
SCHEMBL10914530 0.62 PNMT (0.67) PNMTDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101203505-A Chromane and chromene derivatives and uses thereof WYETH CORP (US) 2008-06-18 CN disclosed