Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28031955 | 0.81 | ELANE (0.36) | MEN1KMT2ACYP3A4KDM4ELMNA | |
| SCHEMBL548262 | 0.74 | MEN1 (0.47) | MEN1KMT2ACYP3A4KDM4ELMNA | |
| SCHEMBL28912629 | 0.74 | KDM4E (0.47) | MEN1KMT2ACYP3A4KDM4ELMNA | |
| SCHEMBL27631295 | 0.73 | CYP3A4 (0.68) | MEN1KMT2ACYP3A4KDM4ELMNA | |
| SCHEMBL18079005 | 0.70 | DDR2 (0.66) | MEN1KMT2ACYP3A4KDM4ELMNA | |
| SCHEMBL548380 | 0.69 | DDR2 (0.42) | MEN1KMT2ACYP3A4KDM4ELMNA | |
| SCHEMBL28031917 | 0.68 | BCL2 (0.39) | MEN1KMT2ACYP3A4KDM4ELMNA | |
| SCHEMBL548145 | 0.67 | MEN1 (0.45) | MEN1KMT2ACYP3A4KDM4ELMNA | |
| SCHEMBL547708 | 0.66 | MEN1 (0.41) | MEN1KMT2ACYP3A4KDM4ELMNA | |
| SCHEMBL11194764 | 0.65 | EDNRA (0.43) | MEN1KMT2AKDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101891728-B | Scutellarin aglycone derivative and preparation method and application thereof | UNIV NANJING CHINESE MEDICINE | 2012-05-23 | — | — | CN | disclosed |
| CN-101337956-B | Scutellarein carbamate derivates, preparation method and application thereof | UNIV SICHUAN | 2011-03-16 | — | — | CN | disclosed |
| CN-101891728-A | Scutellarein derivative as well as preparation method and application thereof | UNIV NANJING CHINESE MEDICINE | 2010-11-24 | — | — | CN | disclosed |
| CN-101337956-A | Scutellarein carbamate derivates, preparation method and application thereof | UNIV SICHUAN (CN) | 2009-01-07 | — | — | CN | disclosed |