Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28031917 | 0.86 | BCL2 (0.39) | BCL2MCL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL27726508 | 0.81 | MEN1 (0.38) | ELANECA1CA2ALDH1A1KDM4E | |
| SCHEMBL547866 | 0.74 | CA1 (0.39) | CA1CA2ALDH1A1KDM4EMEN1 | |
| SCHEMBL29793488 | 0.67 | PTPN1 (0.39) | CA1CA2ALDH1A1KDM4EMEN1 | |
| SCHEMBL548670 | 0.67 | PTPN1 (0.39) | CA1CA2ALDH1A1KDM4EMEN1 | |
| SCHEMBL28912629 | 0.66 | KDM4E (0.47) | CA1CA2ALDH1A1KDM4EMEN1 | |
| SCHEMBL27631295 | 0.65 | CYP3A4 (0.68) | CA1CA2ALDH1A1KDM4EMEN1 | |
| SCHEMBL548149 | 0.65 | MEN1 (0.42) | CA1CA2ALDH1A1KDM4EMEN1 | |
| SCHEMBL11563555 | 0.65 | CA1 (0.49) | CA1CA2ALDH1A1KDM4EMEN1 | |
| SCHEMBL548288 | 0.64 | MEN1 (0.39) | CA1CA2ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102827131-B | Isoflavones amino formate compounds, Preparation Method And The Use | SICHUAN UNIVERSITY (CN) | 2015-09-23 | — | — | CN | disclosed |