Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 9/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 9/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2769634 | 0.99 | ALDH1A1 (0.38) | TSHRALDH1A1MAPK1HSD17B10LMNA | |
| SCHEMBL2768698 | 0.85 | GRIN2D (0.38) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL2769222 | 0.85 | GRIN2D (0.42) | TSHRALDH1A1HSD17B10USP2ALOX15 | |
| Hydrochloric Acid SCHEMBL2769473 | 0.84 | GRIN2D (0.37) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL2770113 | 0.84 | GRIN2D (0.41) | TSHRALDH1A1HSD17B10USP2ALOX15 | |
| SCHEMBL2769105 | 0.83 | HSD17B10 (0.41) | TSHRALDH1A1MAPK1HSD17B10NPC1 | |
| SCHEMBL15104274 | 0.83 | GRIN2D (0.40) | TSHRALDH1A1MAPK1HSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL2768812 | 0.82 | HSD17B10 (0.41) | TSHRALDH1A1MAPK1HSD17B10NPC1 | |
| Hydrochloric Acid SCHEMBL3595126 | 0.82 | GRIN2D (0.39) | TSHRALDH1A1MAPK1HSD17B10LMNA | |
| SCHEMBL2769005 | 0.80 | MAPT (0.41) | ALDH1A1MAPK1MAPTPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805177-B9 | PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2010-09-15 | — | — | EP | claimed |
| EP-1805177-B1 | PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2010-04-28 | — | — | EP | claimed |