Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | PKLR | P30613 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2899883 | 0.80 | HTR6 (0.71) | HTR6SMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL10326743 | 0.80 | HTR6 (0.76) | HTR6SMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL2900833 | 0.79 | HTR6 (0.78) | HTR6SMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL2909209 | 0.78 | HTR6 (0.73) | HTR6SMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL10326883 | 0.77 | HTR6 (0.72) | HTR6SMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL2907151 | 0.76 | HTR6 (0.64) | HTR6SMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL2906939 | 0.76 | HTR6 (1.00) | HTR6SMN1; SMN2LMNAPKMPKLR | |
| SCHEMBL27748109 | 0.75 | HTR6 (0.66) | HTR6SMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL13297277 | 0.75 | HTR6 (0.68) | HTR6SMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL2905648 | 0.73 | HTR6 (0.72) | HTR6SMN1; SMN2LMNAPKMPKLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101356149-A | Indene derivatives, their preparation and use as medicaments | ESTEVE LABOR DR (ES) | 2009-01-28 | — | — | CN | disclosed |