Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.56 |
| ▸ | MMP9 | P14780 | 2/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | MMP7 | P09237 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7889219 | 0.88 | MMP1 (0.57) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL1947519 | 0.88 | MMP1 (0.57) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL4037002 | 0.88 | MMP1 (0.62) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL4035557 | 0.88 | MMP1 (0.62) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL4038681 | 0.88 | MMP1 (0.62) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL14400848 | 0.87 | MMP1 (0.56) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL763824 | 0.87 | MMP1 (0.56) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL1467589 | 0.87 | MMP1 (0.51) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL1467588 | 0.87 | MMP1 (0.51) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL309055 | 0.86 | MMP1 (0.55) | MMP1MMP9MMP3MMP7MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101356164-A | Novel compounds | ASTRAZENECA AB (SE) | 2009-01-28 | — | — | CN | disclosed |