Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.52 |
| ▸ | PPARA | Q07869 | 11/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.46 |
| ▸ | PTGES | O14684 | 3/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745987 | 0.82 | ALDH1A1 (0.63) | TLR8CNR2CNR1 | |
| SCHEMBL10769541 | 0.79 | PTPN11 (0.60) | CNR2CNR1 | |
| SCHEMBL1165782 | 0.79 | CYSLTR2 (0.59) | PPARGPPARAALOX5PTGES | |
| SCHEMBL4396853 | 0.79 | CNR2 (0.51) | PPARGPPARATLR8CNR2CNR1 | |
| SCHEMBL11058906 | 0.79 | CYSLTR2 (0.62) | PPARGPPARA | |
| SCHEMBL10453920 | 0.78 | PTPN11 (0.62) | PPARGPPARA | |
| SCHEMBL4041854 | 0.78 | CYSLTR2 (0.61) | PPARGPPARAALOX5PTGES | |
| SCHEMBL5933091 | 0.78 | CNR2 (0.50) | PPARGPPARATLR8CNR2CNR1 | |
| SCHEMBL5933107 | 0.78 | CNR2 (0.50) | PPARGPPARATLR8CNR2CNR1 | |
| SCHEMBL5861883 | 0.78 | MEN1 (0.61) | PPARGPPARATLR8CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101186598-A | 1-oxy-acetyl inula Britannica lactone derivative, preparation method thereof and application of the same in preparing cancer-curing medicine | UNIV HEBEI MEDICAL (CN) | 2008-05-28 | — | — | CN | disclosed |