Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CTSD | P07339 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18880248 | 0.90 | TDP1 (0.50) | TDP1ALDH1A1CTSDHSD17B10L3MBTL1 | |
| SCHEMBL20926000 | 0.88 | SMN1; SMN2 (0.52) | TDP1ALDH1A1CTSDL3MBTL1MAPK1 | |
| SCHEMBL22732504 | 0.88 | SMN1; SMN2 (0.52) | TDP1ALDH1A1CTSDL3MBTL1MAPK1 | |
| SCHEMBL3091778 | 0.88 | SMN1; SMN2 (0.52) | TDP1ALDH1A1CTSDL3MBTL1MAPK1 | |
| SCHEMBL22367012 | 0.88 | SMN1; SMN2 (0.52) | TDP1ALDH1A1CTSDL3MBTL1MAPK1 | |
| SCHEMBL24949035 | 0.88 | SMN1; SMN2 (0.52) | TDP1ALDH1A1CTSDL3MBTL1MAPK1 | |
| SCHEMBL20892706 | 0.88 | SMN1; SMN2 (0.52) | TDP1ALDH1A1CTSDL3MBTL1MAPK1 | |
| SCHEMBL22792525 | 0.88 | SMN1; SMN2 (0.52) | TDP1ALDH1A1CTSDL3MBTL1MAPK1 | |
| SCHEMBL19366413 | 0.77 | MAOB (0.35) | TDP1ALDH1A1CTSDCYP3A4MEN1 | |
| SCHEMBL236978 | 0.76 | CARM1 (0.52) | TDP1ALDH1A1CTSDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101594866-B | Topical formulations | HELPERBY THERAPEUTICS LTD. (GB) | 2014-10-22 | — | — | CN | disclosed |
| CN-101351203-B | Application of pyrroloquinoline compound in killing clinically latent microorganisms | HELPERBY THERAPEUTICS LTD | 2013-12-04 | — | — | CN | disclosed |
| CN-101594866-A | The preparation of local usefulness | HELPERBY THERAPEUTICS LTD (GB) | 2009-12-02 | — | — | CN | disclosed |
| CN-101351203-A | Application of pyrroloquinoline compound in killing clinically latent microorganisms | HELPERBY THERAPEUTICS LTD (GB) | 2009-01-21 | — | — | CN | disclosed |