Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22792525 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2EPHX2EPHX1RAB9ATDP1 | |
| SCHEMBL20892706 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2EPHX2EPHX1RAB9ATDP1 | |
| SCHEMBL22732504 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2EPHX2EPHX1RAB9ATDP1 | |
| SCHEMBL3091778 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2EPHX2EPHX1RAB9ATDP1 | |
| SCHEMBL20926000 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2EPHX2EPHX1RAB9ATDP1 | |
| SCHEMBL24949035 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2EPHX2EPHX1RAB9ATDP1 | |
| SCHEMBL18880248 | 0.98 | TDP1 (0.50) | SMN1; SMN2EPHX2EPHX1RAB9ATDP1 | |
| SCHEMBL27727490 | 0.88 | TDP1 (0.55) | SMN1; SMN2EPHX2EPHX1RAB9ATDP1 | |
| SCHEMBL23441678 | 0.83 | RAB9A (0.54) | SMN1; SMN2EPHX2EPHX1RAB9AALDH1A1 | |
| SCHEMBL15677756 | 0.81 | RAB9A (0.53) | SMN1; SMN2EPHX1RAB9AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3875451-A1 | TLR8 AGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2021-09-08 | — | — | EP | disclosed |
| EP-3434668-B1 | INDOLO-SUBSTITUTED-PIPERIDINE COMPOUNDS AS ESTROGEN RECEPTOR DEGRADING AGENT | LUOXIN PHARMACEUTICAL SHANGHAI CO LTD (CN) | 2020-08-26 | — | — | EP | disclosed |