Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CCNK | O75909 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | VCP | P55072 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5119711 | 1.00 | ALDH1A1 (0.57) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL5131839 | 0.87 | CCNK (0.50) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL28773998 | 0.81 | CCNK (0.53) | CCNKCDK9NPY5RAXLMKNK1 | |
| SCHEMBL5950946 | 0.80 | NPY5R (0.60) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL5950947 | 0.80 | ALDH1A1 (0.47) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL5126612 | 0.79 | ALDH1A1 (0.57) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL5126614 | 0.79 | ALDH1A1 (0.57) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL5131411 | 0.79 | NPY5R (0.61) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL27707666 | 0.79 | NPY5R (0.61) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL14276500 | 0.77 | ALDH1A1 (0.48) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101203499-A | Alkyl sulfonamide derivatives | LUNDBECK AS CO H (DK) | 2008-06-18 | — | — | CN | claimed |
| CN-101203499-A | Alkyl sulfonamide derivatives | LUNDBECK AS CO H (DK) | 2008-06-18 | — | — | CN | disclosed |